Amy (Amy Schumer) is a single girl living the life in Manhattan. Well-trained into shunning monogamy by her offensive, lovable father (Colin Quinn) who a couple of decades ago abandoned Amy, her sister Kim and their mother, she works at a sleazy men’s magazine by day and is into some serious bed-hopping at night. She uses men as one does tissues, rumpling them into a ball and tossing them in a corner when she’s done.